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Top MLB DFS Start‘em/Sit‘em Lineups For June 22nd

Jordan Ramos
Atlanta Braves at Bristol Motor Speedway

A new week is here, and fantasy players could win cash prizes with Monday’s top MLB DFS lineup and fantasy stacks. Monday’s slate of games will start the new week with a bang and help fantasy players win cash prizes. A new week is here, and fantasy players could win cash prizes with today’s top MLB DFS lineup and fantasy stacks.

Monday’s slate of 13 games will start the week with a bang for today’s fantasy players, including the New York Mets starting a series against the Chicago Cubs. Another game where fantasy players could win cash prizes in today’s top MLB DFS lineups could be the New York Yankees taking on the Detroit Tigers. 

With a new week starting, fantasy players could win cash prizes with today’s top MLB DFS lineup and fantasy stacks.

June 22nd Top MLB DFS Lineup Starters 

1B Alec Burleson, Arizona Diamondbacks at St. Louis Cardinals ($4,400 – DraftKings/$3,500-FanDuel)

To start Monday’s slate of games, Alec Burleson should be in your top MLB DFS lineups against the Diamondbacks. In a win against the Royals, Burleson went 3-for-5 with an RBI triple and a walk. 

Burleson has been having a strong season, and could deliver another solid performance. DFS players could see a multi-RBI game from the Cardinals veteran slugger. 

OF Michael Conforto, Chicago Cubs at New York Mets ($3,700 – DraftKings/2,500-Fanduel)

Michael Conforto of the Chicago Cubs should be in today’s top MLB DFS lineups against the Mets. In the loss to the Blue Jays, Conforto did not make an appearance. 

Conforto has been having a rough stretch of games, but could have a strong game against the Mets. DFS players could see a multi-hit game from the Cubs veteran slugger. 

OF Michael Harris II, Atlanta Braves at San Diego Padres ($4,200 – DraftKings/3,300-Fanduel)

The last player to add to your fantasy lineups is Michael Harris II of the Atlanta Braves, to start the week. In the loss to the Brewers, Harris went 1-for-4 with a double, a strikeout, and a stolen base. 

Harris has been having a strong bounce-back season and could have another solid performance. Fantasy players could see a multi-RBI game from the Braves veteran star outfielder. 

June 22nd Top MLB DFS Lineup Benchwarmers 

2B Fernando Tatis Jr., Cleveland Guardians at Houston Astros ($4,900 – DraftKings/$3,400-FanDuel)

For today’s top MLB DFS benchwarmers, Fernando Tatis Jr is the first player fantasy players should add to their fantasy bench. In the crushing loss to the Rangers, Tatis went 1-for-1 in the close loss. 

Tatis Jr has been sluggish this season and could have another poor game tonight. Fantasy players could see a hitless game from the Padres superstar slugger. 

SS Zach Neto, Baltimore Orioles at Los Angeles Angels ($5,300 – DraftKings/3,600-Fanduel)

Zach Neto of the Los Angeles Angels is another player who should be on your fantasy bench to start the week. In the win against the Athletics, Neto went 1-for-5 with a two-run home run and two strikeouts. 

Neto has been having a strong power season but could have a poor game against the Orioles. DFS players could see a hitless game from the Angels veteran star. 

3B Bo Bichette, Chicago Cubs at New York Mets ($4,200 – DraftKings/$2,900-Fanduel) 

Bo Bichette, of the New York Mets, should be the last player on your top MLB DFS bench for Monday’s game against the Cubs. In the loss to the Phillies, Bichette went 0-for-4 with two strikeouts.

Bichette has been struggling with one hit in his past three games. Fantasy players could see a multi-strikeout game from the Mets star infielder. 

 Total Apex Media Stack Of The Day

top mlb dfs
May 5, 2025; Bronx, New York, USA; San Diego Padres outfielder Fernando Tatis Jr. (23) reacts after striking out against the New York Yankees during the third inning at Yankee Stadium. Mandatory Credit: John Jones-Imagn Images

Monday’s top MLB DFS stack for today’s slate should be the Cincinnati Reds’ Blake Dunn, JJ Bleday, and Sal Stewart. The Reds have been on a hot streak and could have a strong game tonight for fantasy players. With the week on a strong start, fantasy players could win cash prizes with the Reds for tonight’s top MLB DFS lineup stack. 

To kickstart tonight’s top MLB DFS lineup stack, fantasy players should have Horwitz in tonight’s stack. In the win against the Yankees, Dunn went 2-for-4 with a strikeout and a walk. Dunn has been having a breakout season for the Reds, and could have a strong game against the Brewers. Fantasy players could see a multi-hit game from the Reds emerging star outfielder.

Another player for tonight’s lineup stack should be Bleday, who could have a bounce-back game. In the win against the Yankees, Bleday went 0-for-3. Bleday has been having a breakout season for the Reds and could bounce back from a poor performance. DFS players could see a multi-hit game from the Reds star outfielder. 

The last player for tonight’s top MLB DFS lineup stack should be Stewart, who could have a strong game for fantasy players. In the win against the Yankees, Stewart went 1-for-4 with a strikeout. Stewart has been having a strong rookie season, and could deliver a great performance tonight. DFS players could see a multi-RBI game from the Reds’ emerging star infielder. With the new week here, fantasy players could win cash prizes with today’s top MLB DFS lineups and fantasy stacks. 

Jordan Ramos is a journalism graduate writing for sports, betting, fantasy and other interests. Jordan has knowledge of New York sports for the last 15 years, with baseball, football, and basketball being his main topics, along with gaming, news writing, and media studies.