Top MLB DFS Start‘em/Sit‘em Lineups For June 21st

The weekend is heating up, and fantasy players could win cash prizes with today’s top MLB DFS lineup and fantasy stacks. Sunday’s full slate of games will end the weekend with a bang for fantasy lineups and stacks. With the weekend ending, fantasy players could win cash prizes with today’s top MLB DFS lineup and fantasy stacks.

Sunday’s slate of 15 games will end the weekend in style with the Philadelphia Phillies ending their series against the New York Mets. Another game where fantasy players could win cash prizes today should be the Texas Rangers ending their home series against the San Diego Padres.

The weekend is ending with style, and fantasy players could win cash prizes with today’s top MLB DFS lineup and fantasy stacks.

June 21st Top MLB DFS Lineup Starters

1B Jac Caglianone, St. Louis Cardinals at Kansas City Royals ($4,200 – DraftKings/$2,800-FanDuel)

To start Sunday’s slate of games, Jac Caglianone should be in your top MLB DFS lineups against the Royals. In the win against the Cardinals, Caglianone went 2-for-4 with a home run, two RBIs, and a strikeout.

Caglianone has been having a strong June, with four hits in his past three games and could have another strong game. Fantasy players could see another home run from the Royals slugger.

2B Xavier Edwards, San Francisco Giants at Miami Marlins ($4,300 – DraftKings/3,200-Fanduel)

Xavier Edwards of the Miami Marlins should be in today’s top MLB DFS lineups against the Giants. In the win against the Giants, Edwards went 0-for-5 in the close win.

Edwards is having a strong season for the Marlins, and could have a bounce-back game today. DFS players could see a multi-RBI game from the Marlins emerging star infielder.

3B Kazuma Okamoto, Toronto Blue Jays at Chicago Cubs ($3,700 – DraftKings/3,100-Fanduel)

The last player to add to your fantasy lineups is Kazuma Okamoto of the Toronto Blue Jays, to end the weekend. In the win against the Cubs, Okamoto went 1-for-3 with a three-run home run.

Okamoto has been sluggish this season but could have another strong performance today. DFS players could see a multi-RBI game from the Blue Jays Japanese star.

June 21st Top MLB DFS Lineup Benchwarmers

OF Yordan Alvarez, Cleveland Guardians at Houston Astros ($6,100 – DraftKings/$4,000-FanDuel)

For today’s top MLB DFS benchwarmers, Yordan Alvarez is the first player fantasy players should add to their fantasy bench. In the loss to the Guardians, Alvarez went 0-for-3.

Alvarez has been playing well this season but could have another rough game against the Guardians pitching staff. DFS players could see a multi-strikeout game from the Astros veteran slugger.

SS Anthony Volpe, Cincinnati Reds at New York Yankees ($3,900 – DraftKings/3,100-Fanduel)

Anthony Volpe of the New York Yankees is another player who should be on your fantasy bench to end the weekend. In a loss to the Reds, Volpe went 1-for-3 with a walk and a stolen base.

Volpe has been playing well this season but could have a rough game against the Reds today. DFS players could see a multi-strikeout game from Volpe.

OF Jordan Walker, St. Louis Cardinals at Kansas City Royals ($5,500 – DraftKings/$3,900-Fanduel)

Jordan Walker, of the St. Louis Cardinals, should be the last player on your top MLB DFS bench for Sunday’s game against the Royals. In the loss to the Royals, Walker went 2-for-3 with an RBI.

Walker has been sluggish this weekend and could have another poor game for fantasy lineups. DFS players could see a multi-strikeout game from the Cardinals emerging star.

Total Apex Media Stack Of The Day

Oct 8, 2025; Bronx, New York, USA; New York Yankees shortstop Anthony Volpe (11) during the third inning of game four of the ALDS round of the 2025 MLB playoffs against the Toronto Blue Jays at Yankee Stadium. Mandatory Credit: Brad Penner-Imagn Images

Sunday’s top MLB DFS stack for today’s slate should be the Cincinnati Reds’ Spencer Steer, Sal Stewart, and Nathaniel Lowe. The Reds are playing decent baseball, and their offense has been heating up this weekend. Fantasy players could win big with the Reds in today’s top MLB DFS lineup stack with the Reds.

The first player for today’s top MLB DFS lineup stack should be Steer, who has been having a breakout season. In the win against the Yankees, Steer went 1-for-5 with a three-run home run, three RBIs, and two strikeouts. Steer has been having a solid season with 12 home runs and could continue his hot hitting. Fantasy players could see a multi-RBI game from the Reds star slugger.

Another player for today’s top MLB DFS lineup stack should be Stewart, who could have another strong performance. In the win against the Yankees, Stewart went 2-for-4 with six RBIs and a strikeout. Stewart is having a great season, and could have another breakout game. Fantasy players could see a multi-RBI game from the Reds emerging star slugger.

The last player for today’s top MLB DFS lineup stack should be Lowe, who could have a solid game against the Yankees. In the win against the Yankees, Lowe went 2-for-3 with a walk and a strikeout. Lowe has been having a solid season for the Reds and could have another solid performance. Fantasy players could see a multi-hit game from the Reds veteran slugger. With the weekend ending, fantasy players could win cash prizes with today’s top MLB DFS lineup and fantasy stacks.