The Colts have surprised many with a strong start to the season, largely thanks to their bold decision to hand the keys to Daniel Jones. On the other side, the Rams look like a top-tier offense again with Matthew Stafford leading a loaded group of weapons. This one has shootout written all over it, which means fantasy managers should be salivating. Expect fireworks in this matchup. Let’s dive into the best plays for Week 4.
Five reasons why Colts QB Daniel Jones has excelled in 2025 – Matt Bowen via ESPN
🔥 Starts
- Daniel Jones (QB, Colts) 🔥
- Jones has been a dual-threat weapon this season, doing damage both through the air and on the ground. Against a Rams defense that has only had one truly dominant showing (versus Houston), Jones should continue his hot streak. His ability to create plays outside of structure makes him a must-start in this matchup.
- Projection: 246 passing yards, 2 TDs, 58 rushing yards, 1 rushing TD
- Jonathan Taylor (RB, Colts) 🔥
- Taylor has looked like his old self again: fast, decisive, and relentless between the tackles. The Rams haven’t shown much resistance against the run, and Indy will lean on Taylor to set the tone early. He’s a locked-in RB1.
- Projection: 19 carries, 104 yards, 1 TD, 2 catches, 18 yards
- Michael Pittman Jr. (WR, Colts) 🔥
- Pittman and Jones are developing chemistry at the perfect time. Pittman has two touchdowns already this year and continues to produce like a WR2 with WR1 upside. Expect him to find the end zone again and put up another strong stat line.
- Projection: 6 catches, 78 yards, 1 TD
- Tyler Warren (TE, Colts) 🔥
- The first-round rookie tight end has been everything the Colts hoped for. Warren has already seen two games with 7+ targets and has emerged as more than just a safety blanket. Look for him to make chunk plays against LA’s linebackers and secondary.
- Projection: 5 catches, 67 yards, 1 TD
- Matthew Stafford (QB, Rams) 🔥
- Stafford continues to prove he’s still got it. Surrounded by weapons, he’s playing with confidence and efficiency. In a potential shootout with the Colts, he’s a rock-solid QB1.
- Projection: 278 passing yards, 2 TDs, 1 INT
Puka and Stafford Connection is on Fire
- Puka Nacua (WR, Rams) 🔥
- Nacua’s breakout has only accelerated with the arrival of Davante Adams. With defenses forced to account for Adams, Nacua has thrived in single coverage. Expect another high-volume day.
- Projection: 8 catches, 91 yards, 1 TD
- Davante Adams (WR, Rams) 🔥
- Adams has shown he still has plenty left in the tank. His precise route running makes him a perfect complement to Nacua, and he’s still a scoring threat every week.
- Projection: 5 catches, 68 yards, 1 TD
- Kyren Williams (RB, Rams) 💪
- Williams has been outstanding in this offense, contributing both on the ground and through the air. With one rushing score and one receiving touchdown already this year, Williams continues to be a reliable flex option with RB2 upside.
- Projection: 14 carries, 63 yards, 1 TD, 3 catches, 26 yards
❄️ Sits
This matchup is stacked with startable players, but the defenses don’t belong anywhere near your fantasy lineup. With two high-powered offenses on the field, expect points and yardage in bunches.
- Colts Defense ❄️
- Projection: 31 points allowed, 1 sack
- Rams Defense ❄️
- Projection: 27 points allowed, 1 sack, 0 turnovers
🌙 Sleeper
- Blake Corum (RB, Rams) 🌙
- Blake Corum is quietly carving out a role behind Kyren Williams, making him a sneaky fantasy dart throw. He’s logged 15 carries on the year with 1 TD, including matching Williams in carries during the Rams’ matchup with the Eagles. Against the Titans, Corum showed burst and toughness, proving he can handle red-zone work if given the chance.
While his volume is volatile, he’s the type of risky flex 💪 play who could find the end zone on limited touches. In deeper leagues or bye-week crunches, Corum offers touchdown upside that could pay off big if he gets a hot hand.
Projected Stat Line:
• 8 carries, 34 yards, 2 receptions, 14 yards, 0.5 TD
Wrap-Up
The Rams vs. Colts game projects as one of the most exciting fantasy matchups of the week. With Daniel Jones, Jonathan Taylor, and Michael Pittman clicking, Indianapolis looks poised to keep pace with Stafford, Nacua, and Adams on the other side. Kyren Williams adds balance as a reliable flex, while rookie Tyler Warren is a breakout tight end to watch. Sit both defenses, and if you’re searching for upside in deeper leagues, Alec Pierce makes sense as a sleeper. Fire up your stars, because this one should deliver plenty of fantasy fireworks.
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