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Indianapolis Colts vs. Jacksonville Jaguars Preview, Prediction & Odds | Week 14, 2025

The Colts and the Jaguars, both sitting at 8-4, are set to collide in a Week 14 showdown with massive implications for the AFC South title. 

Colts
Indianapolis Colts quarterback Daniel Jones (17) walks off the field Sunday, Nov. 30, 2025, after the Indianapolis Colts lost to the Houston Texans 20-16 at Lucas Oil Stadium in Indianapolis. © Christine Tannous/IndyStar / USA TODAY NETWORK via Imagn Images
Indianapolis Colts (8-4) at Jacksonville Jaguars (8-4)
Game Details: Sunday, December 7, 1 p.m. EST
Location: Everbank Stadium
Where to Watch: CBS

Week 14 Matchup

The stakes couldn’t be higher in Jacksonville this Sunday. The Colts and the Jaguars, both sitting at 8-4, are set to collide in a Week 14 showdown with massive implications for the AFC South title. 

Betting Odds

Team Spread Money Line Total
Indianapolis Colts-1.5-126Over 46.5
Jacksonville Jaguars +1.5+108Under 45.5

** Odds Subject to Change – Courtesy of FanDuel**

Tale of The Tape

Indianapolis Team Stats – Avg Per GameJacksonville Jaguars
29.8Points Per Game24.3
241.0Passing Yards Per Game202.8
134.4Rushing Yards Per Game123.3
20.8Opponents Points Per Game Allowed21.1
246.3Opponents Pass Yards Allowed 230.1
98.3Opponents Rush Yards Allowed 82.4

Statistics from various online sources and courtesy of ESPN and FOX Sports

Key Details

Indianapolis Colts

For the Indianapolis Colts, this game is about more than just their record. It’s about exorcising demons. The team hasn’t won a game in Jacksonville since 2015, a staggering losing streak that has haunted the franchise for nearly a decade. Despite the history, this is a different Colts team, one that has found surprising success this season. Quarterback Daniel Jones has been a revelation, but a recent fibula injury could limit the mobility that makes him so dangerous. Indy knows what’s at stake, and they’ll be looking to finally put an end to the “Jacksonville curse.”

Jacksonville Jaguars

The Jaguars are riding a wave of momentum after a decisive 25-3 victory over the Tennessee Titans. However, they are heading into this critical matchup banged up. The Jags’ offense has shown steady improvement, with quarterback Trevor Lawrence noting, “We’ve just been playing better offensively. All year I think we’ve gotten better every week…”  They’ll need that upward trend to continue against a hungry Colts squad.

Prediction

 At a 1.5 spread, Vegas calls this game a toss-up. Jacksonville comes in hot and is at home. The Colts will not break the Duval County streak this year.

Final Pick

Jacksonville Jaguars  +1.5

Over 46.5