|

Top MLB DFS Start‘em/Sit‘em Lineups for August 21st

orioles top mlb dfs

The weekend is officially here, and with August ending soon, fantasy players could win cash prizes in today’s top MLB DFS lineups and fantasy stacks. Friday’s full slate of games will start the weekend of baseball with a bang for fantasy lineup players before the weekend. The weekend is here, and fantasy players could win cash prizes in today’s top MLB DFS lineups and fantasy stacks to kickstart the weekend. 

Friday’s slate of 15 games will start the weekend with a bang, with the New York Mets starting a series against the Chicago White Sox. Another series that could help fantasy players win cash prizes is the Cleveland Guardians taking on the Colorado Rockies. 

The weekend is here, and fantasy players could win cash prizes with today’s top MLB DFS lineups and fantasy stacks. 

August 21st Top MLB DFS Lineup Starters 

1B Josh Bell, Minnesota Twins at San Diego Padres ($3,800 – DraftKings/$2,900-FanDuel)

To start Friday’s slate of games, Josh Bell should be in your top MLB DFS lineups against the Padres. In the win against the Braves, Bell went 1-for-3 with an RBI double and a walk. 

Bell is having a solid season with 17 home runs and 78 RBIs. Fantasy players could see another multi-RBI performance from Bell. 

2B Gleyber Torres, Detroit Tigers at Kansas City Royals ($4,300 – DraftKings/3,100-Fanduel)

Gleyber Torres of the Detroit Tigers should be in today’s top MLB DFS lineups to start the weekend against the Royals. During a loss to the Pirates, Torres went 1-for-3 with an RBI, a walk, and a strikeout. 

Torres has been playing well with an ongoing six-game hitting streak. Fantasy players could see a multi-RBI performance against the Royals tonight. 

3B Bo Bichette, Atlanta Braves at Chicago White Sox ($4,300 – DraftKings/2,900-Fanduel)

The last player to add to your fantasy lineups is Bo Bichette of the New York Mets to kick off the weekend. In the Mets‘ win against the Padres, Bichette went 0-for-3 with an RBI, a walk, and a strikeout. 

Bichette has been playing well with a seven-game hitting streak before Wednesday. Fantasy players could see a multi-hit game from Bichette tonight. 

August 21st MLB DFS Lineup Benchwarmers 

SS Gunnar Henderson, Tampa Bay Rays at Baltimore Orioles ($5,100 – DraftKings/$3,100-FanDuel)

For today’s top MLB DFS benchwarmers, Gunnar Henderson is the first player fantasy players should add to their benches for Friday’s games. In the loss to the Yankees, Henderson went 1-for-3 with a walk and two strikeouts. 

Henderson is having a rough season and could struggle against the Rays tonight. Fantasy players could see a hitless performance from Henderson. 

OF Oneil Cruz, Pittsburgh Pirates at Los Angeles Dodgers ($5,900 – DraftKings/3,900-Fanduel)

Oneil Cruz of the Pittsburgh Pirates is another player who should be on your fantasy bench to start the weekend. During a win against the Tigers, Cruz went 1-for-3 with an RBI, a walk, a strikeout, and a stolen base. 

Cruz has been having a rough stretch of games with two hits in his past five games. Fantasy players could see a hitless game from Cruz tonight. 

OF Mike Trout, Los Angeles Angels at Texas Rangers ($5,100 – DraftKings/$3,500-Fanduel) 

Mike Trout, of the Los Angeles Angels, should be the last player on your top MLB DFS bench for Friday’s game against the Rangers. In the win against the Astros, Trout went 0-for-2 with two walks and two strikeouts. 

While Trout is playing well, he is struggling with one hit in his past four games. Fantasy players could see a multi-strikeout game from Trout. 

 Total Apex Media Stack Of The Day

JJ Wetherholt about to take batting practice
Feb 16, 2026; Jupiter, FL, USA; St. Louis Cardinals infielder JJ Wetherholt (77) during spring training workouts at Roger Dean Stadium. Mandatory Credit: Reinhold Matay-Imagn Images

Friday’s top MLB DFS stack for today’s slate should be the St. Louis Cardinals’ JJ Wetherholt, Ivan Herrera, and Jordan Walker. The Cardinals are coming off a solid series against the Reds and could continue their strong hitting today. Fantasy players could win cash prizes with today’s top MLB DFS lineup stacks with the Cardinals. 

The first player for today’s top MLB DFS lineup stack should be Wetherholt, who could have a solid performance. In the win against the Reds, Wetherholt went 1-for-4 with three runs. Wetherholt is having a solid rookie season and could deliver a solid game tonight. Fantasy players could see a multi-RBI game from Wetherholt. 

Another player for today’s fantasy lineup stack should be Herrera, who could have a solid performance. In the win against the Reds, Herrera went 1-for-3 with two walks. Herrera has been having a solid season with a .745 OPS and could have a strong game. Fantasy players could see a multi-hit performance from Herrera tonight. 

The last player for today’s top MLB DFS lineup stack should be Walker, who is having a breakout season. In the win against the Reds, Walker went 1-for-4 with a three-run home run, four RBIs, a walk, and a strikeout. Walker is having a breakout season and could have another solid performance. Fantasy players could see a multi-RBI performance from Walker. With August ending soon, fantasy players could win cash prizes with today’s top MLB DFS lineups and fantasy stacks.