Connor

NFL

Cardinals-49ers game: Connor Carted Off The Field With Leg Injury; Bosa Injures Knee

Don Watz September 21, 2025

Arizona Cardinals RB James Connor left the game in the third quarter against San Francisco with an apparent leg/ankle injury. He was carted off the field.

He left the game with 9 carries for 22 yards. Last week against Carolina, Conner had 11 carries for 34 yards and a touchdown while bringing in his only target for 18 yards in Sunday’s 27-22 win over Carolina. For the season, Connor had 23 carries for 73 yards and just one touchdown. 5 receptions for 23 yards.

James Connor injury looks like a dislocated knee or something broken prayers up 🙏🏼 pic.twitter.com/BQuLcwK7sh

— Football Fanatics (@FFB_Fanatics) September 21, 2025

Nick Bosa Injures Knee – Out For the Rest of the Game

In the second quarter of the same game, Nick Bosa left with an knee injury. By halftime, the FOX broadcast indicated the Bosa is out for the rest of the game.

Bosa had one tackle in the game. Coming into the game, he had 15 tackles and one quarterback sack.

Bosa — Oct 27, 2024; Santa Clara, California, USA; San Francisco 49ers defensive lineman Nick Bosa (97) celebrates as he leaves the field after the game against the Dallas Cowboys at Levi’s Stadium. Mandatory Credit: Kelley L Cox-Imagn Images

This article will be updated as news is available.

Don Watz

Don recently returned to writing after a hiatus. His work has appeared in numerous publications, including the USA Today, Tallahassee Democrat, Milwaukee Journal Sentinel, Detroit Free Press, and Arizona Republic.